Specifications
Immunogen
Synthetic peptide corresponding to a region between C terminal amino acids 494-543 (AKSFTELARA SVDVDMHMDL HGLFITDMDW DTKKQAASEE QRDRASDCHG) of Human BCMO1 (NP_059125).
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
BCMO1; beta-carotene 15,15-monooxygenase 1; BCDO, BCDO1, beta carotene 15, 15 dioxygenase 1; beta,beta-carotene 15,15-monooxygenase; BCMO; FLJ10730; beta-carotene dioxygenase 1; beta-carotene 15, 15-dioxygenase 1; BCO; BCDO; BCO1; BCDO1;
Product Background
Antigen Description
Symmetrically cleaves beta-carotene into two molecules of retinal. The reaction proceeds in three stages, epoxidation of the 15,15-double bond, hydration of the double bond leading to ring opening, and oxidative cleavage of the diol formed.
Pathway
Metabolic pathways; Metabolism; Metabolism of lipids and lipoproteins; Metabolism of steroid hormones and vitamins A and D; Retinol metabolism; Vitamin A and carotenoid metabolism.
Citations
Publication ()
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COA
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