Anti-BCAN polyclonal antibody (DPABH-01928)
Rabbit anti-Human BCAN (aa 83-262) polyclonal antibody for WB, IHC-P
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Recombinant fragment, corresponding to a region within amino acids 83-262 of Human Brevican (AAH09117).
WB: 1/500 - 1/3,000; IHC-P: 1/100 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
BCAN; brevican; BEHAB; CSPG7; brevican core protein; chondroitin sulfate proteoglycan 7
A tetrasaccharide linker sequence is required for GAG synthesis; Chondroitin sulfate biosynthesis; Degradation of the extracellular matrix; Disease
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Singer, II; Scott, S; et al. Aggrecanase and metalloproteinase-specific aggrecan neo-epitopes are induced in the articular cartilage of mice with collagen II-induced arthritis. OSTEOARTHRITIS AND CARTILAGE 5:407-418(1997).
Westling, J; Gottschall, PE; et al. ADAMTS4 (aggrecanase-1) cleaves human brain versican V2 at Glu(405)-Gln(406) to generate glial hyaluronate binding protein. BIOCHEMICAL JOURNAL 377:787-795(2004).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.