Anti-BBS10 (aa 182-413) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant fragment, corresponding to a sequence within amino acids 182-413 of Human BBS10.

Conjugate

Application Notes

WB: 1/500 - 1/3000;

Alternative Names

BBS10; Bardet-Biedl syndrome 10; C12orf58; Bardet-Biedl syndrome 10 protein;

Entrez Gene ID

UniProt ID

Antigen Description

BBS10 belongs to the TCP-1 chaperonin family. It is a probable molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Defects in BBS10 are the cause of Bardet-Biedl syndrome type 10 (BBS10) [MIM:209900]. Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation.