BBOX1 (NP_003977, 278 a.a. ~ 387 a.a) partial recombinant protein with GST tag. The sequence is IELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDV ITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVENGN
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
Pathway
Carnitine synthesis; Lysine degradation; Metabolism of amino acids and derivatives;
Citations
Publication ()
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