General Notes
This product (Catalog No. DPABH-05142) is a rabbit-derived polyclonal antibody raised against human B4GALT4, targeting the amino acid region 39–142 of the protein. This antibody exhibits cross-reactivity with Human B4GALT4 from mouse and rat. It has been affinity purified by Protein A. This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.
DPABH-05142 is suitable for use in Western blot (WB) (1:1,000–1:6,000), IF/ICC (1:1,000–1:4,000) applications.
DPABH-05142 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
beta4Gal T4; Beta-1,4-GalTase 4; Beta-1,4-galactosyltransferase 4; Beta 1,4 GalTase 4; b4Gal-T4
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