Rabbit Anti-Human B4GALT1 Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Peptide

Conjugate

Application Notes

WB: 1:500-1:2000

General Notes

This product (Catalog No. DPABH-16751) is a rabbit-derived polyclonal antibody raised against human B4GALT1. This antibody exhibits cross-reactivity with Human B4GALT1 from mouse. It has been affinity purified by Protein A. B4GALT1 is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. B4GALT1 is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. B4GALT1 has two isoforms with molecular weights of 44 kda and 43 kda that are localized to the cell surface and Golgi apparatus, respectively.
DPABH-16751 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
DPABH-16751 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

GTB; GT1; GGTB2; beta4Gal T1; Beta 1,4 GalTase 1

Entrez Gene ID

UniProt ID