Anti-B4GALNT3 monoclonal antibody (DCABH-10698) Made to order

Rabbit anti-Human B4GALNT3 monoclonal antibody for WB, ELISA

View other B4GALNT3 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human B4GALNT3 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
B4GALNT3; beta-1,4-N-acetyl-galactosaminyl transferase 3; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2; B4GalNac T3; FLJ16224; FLJ40362
Entrez Gene ID
UniProt ID

Product Background


Gene summary
B4GALNT3 (Beta-1,4-N-Acetyl-Galactosaminyltransferase 3) is a Protein Coding gene. GO annotations related to this gene include acetylgalactosaminyltransferase activity and N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT4. B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al. , 2006 [PubMed 16728562]).
Antigen Description
B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al. , 2006 [PubMed 16728562]). Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N-diacetyllactosediamine formation on gastric mucosa. The function about B4GALNT3 antigen include N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity; acetylgalactosaminyltransferase activity; transferase activity.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Hoon, DSB; Kuo, CT; et al. Ganglioside GM2/GD2 synthetase mRNA is a marker for detection of infrequent neuroblastoma cells in bone marrow. AMERICAN JOURNAL OF PATHOLOGY 159:493-500(2001).

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