Specifications
Species Reactivity
Human; Rat
Immunogen
B4GALNT1 (NP_001469, 30 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
B4GALNT1; beta-1,4-N-acetyl-galactosaminyl transferase 1; GALGT, UDP Gal:betaGlcNAc beta 1,4 N acetylgalactosaminyltransferase transferase 1 , UDP N acetyl alpha D galactosamine:(N acetylneuraminyl) galactosylglucosylceramide N acetylgalactosaminyltransfe
Product Background
Antigen Description
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively.
Pathway
Ganglio Sphingolipid Metabolism, organism-specific biosystem; Glycosphingolipid biosynthesis - ganglio series, organism-specific biosystem; Glycosphingolipid biosynthesis - ganglio series, conserved biosystem; Metabolic pathways, organism-specific biosystem.
Citations
Publication ()
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COA
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