Rabbit Anti-Human B3GNT7 (a.a. 31-164) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human B3GNT7 protein; Source: E. coli derived, PET28a; Tag: 6*His; Domain: 31-164 aa of BC148680

Conjugate

Application Notes

WB: 1:500-1:2000
IHC: 1:100-1:500

General Notes

This product (Catalog No. DPABH-18096) is a rabbit-derived polyclonal antibody raised against human B3GNT7, targeting the amino acid region 31–164 of the protein. This antibody exhibits cross-reactivity with Human B3GNT7 from mouse. It has been affinity purified by Protein A. B3GNT7, the glycosyltransferase gene that was most significantly upregulated by IL-22 treatment, encodes an N-acetylglucosaminyltransferase involved in the biosynthesis of polyLacNAc repeats of keratan sulfate (PMID: 34864058). B3GNT7 was initially identified in 2002 and is notable for high expression in healthy intestinal epithelial cells (PMID: 38886669). Overexpressed B3GNT7 were correlated with poor prognosis in breast cancer patients based on public datasets. B3GNT7 was shown to be a potential biomarker for unfavorable outcomes and therapeutic target of breast cancer (PMID: 37740763).
DPABH-18096 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:100–1:500) applications.
DPABH-18096 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

BGnT7; Beta3Gn-T7; beta3GnT7; Beta-1,3-N-acetylglucosaminyltransferase 7; Beta-1,3-Gn-T7

Entrez Gene ID

UniProt ID