Specifications
Immunogen
A synthetic peptide of human B3GNT5 is used for rabbit immunization.
Target
Alternative Names
B3GNT5; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; B3GN T5; beta3Gn T5; BGnT-5; lc3 synthase; beta-1,3-Gn-T5; lc(3)Cer synthase; lactotriaosylceramide synthase; beta-1,3-N-acetylglucosaminyltransferase 5; beta-1,3-N-acetylglucosaminylt
Product Background
Antigen Description
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids.
Pathway
Glycosphingolipid biosynthesis - lacto and neolacto series, organism-specific biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, conserved biosystem; Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer, organism-specific biosystem; Lc4Cer, conserved biosystem; Glycosphingolipid biosynthesis, neolacto-series, LacCer =>.
Citations
Publication ()
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COA
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