Anti-B3GNT1 monoclonal antibody (DCABH-690)

Mouse anti-Human B3GNT1 monoclonal antibody for ELISA, sELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Species Reactivity
Human
Immunogen
Recombinant fragment: AYVVPWQDPW EPFYVAGGKV PTFDERFRQY GFNRISQACE LHVAGFDFEV LNEGFLVHKG FKEALKFHPQ KEAENQHNKI LYRQFKQELK AKYPNSPRRC, corresponding to C terminal amino acids 316-415 of Human B3GNT with a proprietary tag (NP_006867).
Conjugate
Unconjugated

Applications


Application Notes
Sandwich ELISA: 10 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
B3GNT1; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; B3GNT6, UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 6; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; B3GN T1; BETA3GNTI
Entrez Gene ID
UniProt ID

Product Background


Pathway
Glycosaminoglycan biosynthesis - keratan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - keratan sulfate, conserved biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, organism-specific biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, conserved biosystem; Metabolic pathways, organism-specific biosystem;

Citations


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References


Czeschik, JC; Hehr, U; et al. 160 kb deletion in ISPD unmasking a recessive mutation in a patient with Walker-Warburg syndrome. EUROPEAN JOURNAL OF MEDICAL GENETICS 56:689-694(2013).
Shaheen, R; Faqeih, E; et al. A truncating mutation in B3GNT1 causes severe Walker-Warburg syndrome. NEUROGENETICS 14:243-245(2013).

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