Specifications
Species Reactivity
Dog; Human
Immunogen
Recombinant fragment, corresponding to amino acids 42-309 of Human ATRIP produced in E.coli (NP_569055).
Applications
Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;
Target
Alternative Names
ATRIP; ATR interacting protein; ATR-interacting protein; FLJ12343; MGC20625; MGC21482; MGC26740; ATM and Rad3-related-interacting protein; DKFZp762J2115;
Product Background
Antigen Description
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Pathway
Activation of ATR in response to replication stress, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; DNA damage response, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; G2/M Checkpoints, organism-specific biosystem;
Citations
Publication ()
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COA
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