Anti-ATG7 monoclonal antibody, clone FQS7362 Knockout Validated

Name: Anti-ATG7 monoclonal antibody, clone FQS7362
SKU: DCABH-2764
Rating: 5 (1 reviews)

Rabbit anti-Human ATG7 monoclonal antibody for WB, ICC/IF

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Clone

FQS7362

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide corresponding to residues in the Human Apg7 protein (UniProt O95352).

Conjugate

Unconjugated

Applications

Application Notes

WB: 1/10000 - 1/50000; ICC/IF: 1/100 - 1/250;

Target

Alternative Names

ATG7; ATG7 autophagy related 7 homolog (S. cerevisiae); APG7 autophagy 7 like (S. cerevisiae) , APG7L; ubiquitin-like modifier-activating enzyme ATG7; DKFZp434N0735; GSA7; hAGP7; autophagy-related protein 7; ATG12-activating enzyme E1 ATG7; ubiquitin acti

Entrez Gene ID

10533

UniProt ID

O95352

Product Background

Antigen Description

Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3.

Pathway

Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Regulation of autophagy, organism-specific biosystem;

Citations