Anti-ATAD3A monoclonal antibody (DCABH-10650) Made to order

Rabbit anti-Human ATAD3A monoclonal antibody for WB, ELISA

View other ATAD3A antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human ATAD3A is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
ATAD3A; ATPase family, AAA domain containing 3A; ATPase family AAA domain-containing protein 3A; FLJ10709; FLJ35514
Entrez Gene ID
UniProt ID

Product Background


Gene summary
ATAD3A (ATPase Family, AAA Domain Containing 3A) is a Protein Coding gene. An important paralog of this gene is ATAD3C. ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al. , 2007 [PubMed 17210950]).
Antigen Description
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al. , 2007 [PubMed 17210950]). Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. The function about ATAD3A antigen include ATP binding; nucleoside-triphosphatase activity; nucleotide binding.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Li, SJ; Lamarche, F; et al. Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues. GENE 535:60-69(2014).
Hubstenberger, A; Merle, N; et al. Topological analysis of ATAD3A insertion in purified human mitochondria. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 42:143-150(2010).

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