Anti-ASIC5 (aa 387-414) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide within Human ACCN5 aa 387-414 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q9NY37

Conjugate

Application Notes

WB: 1/100 - 1/500;

Alternative Names

ASIC5; acid-sensing (proton-gated) ion channel family member 5; INAC; ACCN5; HINAC; acid-sensing ion channel 5; human intestine Na(+) channel; amiloride-sensitive sodium channel; amiloride-sensitive cation channel 5, intestinal;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.

Pathway

Inflammatory mediator regulation of TRP channels; Ion channel transport; Transmembrane transport of small molecules.