Anti-ASCL2 monoclonal antibody (DCABH-10638) Made to order

Rabbit anti-Human ASCL2 monoclonal antibody for WB, ELISA

View other ASCL2 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human ASCL2 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
ASCL2; achaete-scute complex homolog 2 (Drosophila); achaete scute complex (Drosophila) homolog like 2 , achaete scute complex like 2 (Drosophila); achaete-scute homolog 2; ASH2; bHLHa45
Entrez Gene ID
UniProt ID

Product Background


Gene summary
ASCL2 (Achaete-Scute Family BHLH Transcription Factor 2) is a Protein Coding gene. Diseases associated with ASCL2 include beckwith-wiedemann syndrome. Among its related pathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Human Early Embryo Development. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is ASCL4. This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Antigen Description
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5-CANNTG-3). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Achaete-scute complex homolog 2 (Drosophila), also known as ASCL2, is an imprinted human gene. The function about ASCL2 antigen include E-box binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity.

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Dessein, AF; Stechly, L; et al. Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells. CANCER RESEARCH 70:4644-4654(2010).
Liu, XD; Chen, X; et al. Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development. NATURE 507:513-+(2014).

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