ARSE (NP_000038, 490 a.a. ~ 589 a.a) partial recombinant protein with GST tag. The sequence is GACYGRKVCPCFGEKVVHHDPPLLFDLSRDPSETHILTPASEPVFYQVMERVQQAVWEHQ RTLSPVPLQLDRLGNIWRPWLQPCCGPFPLCWCLREDDPQ
Arylsulfatase E is a member of the sulfatase family. It is glycosylated postranslationally and localized to the golgi apparatus. Sulfatases are essential for the correct composition of bone and cartilage matrix. X-linked chondrodysplasia punctata, a disease characterized by abnormalities in cartilage and bone development, has been linked to mutations in this gene. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the Y chromosome.
Pathway
Estrogen metabolism; Metabolism; Metabolism of proteins; Post-translational protein modification
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