ARPC5L (actin related protein 2/3 complex, subunit 5-like) is a protein-coding gene. Diseases associated with ARPC5L include shigellosis, and among its related super-pathways are Development Slit-Robo signaling and Regulation of Actin Cytoskeleton. GO annotations related to this gene include actin binding. An important paralog of this gene is ARPC5. May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Pathway
Bacterial invasion of epithelial cells; Fc gamma R-mediated phagocytosis;Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton; Salmonella infection; Shigellosis;
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