Rabbit Anti-Human ARHGEF11 (N-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthesized peptide derived from N-terminal of human ARHGEF11.

Conjugate

Application Notes

WB: 1:500-1:3000

General Notes

This product (Catalog No. DPABH-24574) is a rabbit-derived IgG polyclonal antibody raised against human ARHGEF11. It has been affinity purified by protein A. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
DPABH-24574 is suitable for use in Western blot (WB) (1:500–1:3,000) application.
DPABH-24574 is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ARHGB; glutamate transporter EAAT4-associated protein 48; GTRAP48; PDZ-RhoGEF; rho guanine exchange factor (GEF) 11

Entrez Gene ID

UniProt ID