Synthetic peptide corresponding to a region within internal sequence amino acids 184-233 (PRPPLPTQQF GVSLQYLKDK NQGELIPPVL RFTVTYLREK GLRTEGLFRR) of Human ARHGAP8 (NP_851852).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
ARHGAP8; Rho GTPase activating protein 8; PP610; BPGAP1; rho GTPase-activating protein 8; rho-type GTPase-activating protein 8; BCH domain-containing Cdc42GAP-like protein; BNIP-2 and Cdc42GAP homology domain-containing, proline-rich and Cdc42GAP-like pro
ARHGAP8 is a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants.
Pathway
Regulation of RhoA activity; Signal Transduction.
Citations
Publication ()
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COA
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