RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]
Pathway
Regulation of CDC42 activity; Regulation of RAC1 activity; Rho GTPase cycle; Signal Transduction; Signaling by Rho GTPases.
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