Anti-AREG monoclonal antibody (DCABY-3963)

Mouse Anti-Human AREG monoclonal antibody for WB, ELISA(Cap), Neut Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
42332
Species Reactivity
Human
Immunogen
E. coli-derived recombinant human Amphiregulin
Conjugate
Unconjugated

Applications


Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-3963 - DPABY-442
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
AREG; amphiregulin; AR; SDGF; AREGB; CRDGF
Entrez Gene ID
UniProt ID

Product Background


Pathway
ErbB receptor signaling network; ErbB signaling pathway; FSH signaling pathway; Hippo signaling pathway;

Citations


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References


Chang, MH; Ahn, HK; et al. Clinical Impact of Amphiregulin Expression in Patients With Epidermal Growth Factor Receptor (EGFR) Wild-Type Nonsmall Cell Lung Cancer Treated With EGFR-Tyrosine Kinase Inhibitors. CANCER 117:143-151(2011).
Minjgee, M; Toulany, M; et al. K-RAS(V12) INDUCES AUTOCRINE PRODUCTION OF EGFR LIGANDS AND MEDIATES RADIORESISTANCE THROUGH EGFR-DEPENDENT AKT SIGNALING AND ACTIVATION OF DNA-PKCS. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81:1506-1514(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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