Rabbit Anti-Human AP4B1 (a.a. 1-351) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human AP4B1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-351 aa of BC014146

Conjugate

Application Notes

WB: 1:500-1:1000
IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate

General Notes

This product (Catalog No. DPABH-24645) is a rabbit-derived polyclonal antibody raised against human AP4B1, targeting the amino acid region 1–351 of the protein. It has been affinity purified by Protein A. Adaptor protein (AP) complex is a component of intracellular protein transport. The AP4 complex is involved in sorting transmembrane cargo proteins into transport vesicles for trans-Golgi network export. AP4B1 is a member of the AP4 complex, which also includes AP4E1, AP4M1 and AP4S1. Loss-of-function variants in any of these four members can lead to AP-4-associated hereditary spastic paraplegia (HSP), a neurodegenerative disorder (PMID: 30543385).
DPABH-24645 is suitable for use in Western blot (WB) (1:500–1:1,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate) applications.
DPABH-24645 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Adaptor-related protein complex 4 subunit beta-1; AP-4 adaptor complex subunit beta; AP-4 complex subunit beta-1; Beta subunit of AP-4; Beta4-adaptin

Entrez Gene ID

UniProt ID