A region within synthetic peptide: IIEILSGRTS DERQQIKQKY KATYGKELEE VLKSELSGNF EKTALALLDR, corresponding to N terminal amino acids 37-86 of Human Annexin A13
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]
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