General Notes
This product (Catalog No. DPABH-06000) is a rabbit-derived polyclonal antibody raised against human ANKRD16, targeting the amino acid region 8–361 of the protein. This antibody exhibits cross-reactivity with Human ANKRD16 from mouse. It has been affinity purified by Protein A. ANKRD16, a vertebrate-specific protein that contains ankyrin repeats, binds directly to the catalytic domain of AlaRS. Serine that is misactivated by AlaRS is captured by the lysine side chains of ANKRD16, which prevents the charging of serine adenylates to tRNAAla and precludes serine misincorporation in nascent peptides. The deletion of Ankrd16 in the brains of Aarssti/sti mice causes widespread protein aggregation and neuron loss (PMID: 29769718).
DPABH-06000 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:250–1:1,000), IF/ICC (1:50–1:500) applications.
DPABH-06000 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
Publication 
Loading ......
