Anti-AMPD1 polyclonal antibody

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to human AMPD1. The sequence is C-HMFSSKSPKPQE

Conjugate

Application Notes

ELISA: 1:1000. & The optimal working dilution should be determined by the end user.

Alternative Names

AMPD1; adenosine monophosphate deaminase 1; MAD; MADA; MMDD; AMP deaminase 1; AMPD; skeletal muscle AMPD; myoadenylate deaminase; adenosine monophosphate deaminase-1 (muscle); adenosine monophosphate deaminase 1 (isoform M);

Entrez Gene ID

UniProt ID

Antigen Description

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]

Pathway

Metabolism; Purine metabolism; Purine salvage;