Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant fragment within Human JAML aa 250 to the C-terminus. The exact sequence is proprietary.Database link: Q86YT9
Applications
Application Notes
Flow Cyt: 1/160; WB: 1/1000 - 1/10000; IP: 1/40 - 1/60.
Target
Alternative Names
AMICA1; adhesion molecule, interacts with CXADR antigen 1; junctional adhesion molecule-like; AMICA; Gm638; adhesion molecule AMICA; junctional adhesion molecule; dendritic cell-specific protein CREA7-1; dendritic-cell specific protein CREA7-1; dendritic-
Product Background
Antigen Description
May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.
Pathway
Adaptive Immune System, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Citations
Publication ()
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COA
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