Anti-SERPINA1 monoclonal antibody (CABT-49282MH)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
1AT
Species Reactivity
Human
Immunogen
Purified human serum alpha-1-antitrypsin
Conjugate
Unconjugated

Target


Alternative Names
SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; PI; A1A; AAT; PI1
Entrez Gene ID
UniProt ID
P01009

Product Background


Pathway
Complement and Coagulation Cascades; Complement and coagulation cascades; FOXA1 transcription factor network; Hemostasis; Platelet activation, signaling and aggregation; Platelet degranulation; Response to elevated platelet cytosolic Ca2+;

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Nakayama, R; Kuroda, J; et al. Suppression of SERPINA1-albumin complex formation by galectin-3 overexpression leads to paracrine growth promotion of chronic myelogenous leukemia cells. LEUKEMIA RESEARCH 38:103-108(2014).
Miller, GS; Zoratti, GL; et al. HATL5: A Cell Surface Serine Protease Differentially Expressed in Epithelial Cancers. PLOS ONE 9:-(2014).

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