DEPC-1 (AAH15155, 1 a.a. ~ 139 a.a) full-length recombinant protein with GST tag. The sequence is MEPNPHWHPVLRTLKNRIEENTGHTFNSLLCNLYRNEKDSVDWHSDDEPSLGRCPIIASL SFGATRTFEMRKKPPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYHSRE PRVNLTFRTVYPDPRGAPW
Conjugate
Unconjugated
Target
Alternative Names
ALKBH3; alkB, alkylation repair homolog 3 (E. coli); ABH3; PCA1; DEPC1; DEPC-1; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; prostate cancer antigen 1; prostate cancer antigen-1; alkylated DNA repair protein alkB homolog 3;
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]
Pathway
ABH3 mediated Reversal of Alkylation Damage; DNA Repair.
Citations
Publication ()
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