Anti-ALG10 (aa 193-242) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to a region within internal sequence amino acids 193-242 (AVFCAGNVIA QKLTEAWKTE LQKKEDRLPP IKGPFAEFRK ILQFLLAYSM) of Human ALG10 (NP_116223).

Conjugate

Application Notes

WB: 1 μg/ml.

Alternative Names

ALG10; asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); asparagine linked glycosylation 10, alpha 1,2 glucosyltransferase homolog (yeast); dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; derepress

Entrez Gene ID

UniProt ID

Antigen Description

ALG10 encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go(EAG) potassium ion channel.

Pathway

Asparagine N-linked glycosylation; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein; Metabolic pathways; Metabolism of proteins; N-Glycan biosynthesis; N-glycan precursor biosynthesis;