Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ALDH4A1 aa 550 to the C-terminus. The exact sequence is proprietary.Database link: P30038
Applications
Application Notes
WB: 1/10000 - 1/50000; IHC-P: 1/100 - 1/250; ICC/IF: 1/1000; IP: 1/40 - 1/60;
Target
Alternative Names
ALDH4A1; aldehyde dehydrogenase 4 family, member A1; ALDH4; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; P5CDh; P5C dehydrogenase; aldehyde dehydrogenase family 4 member A1; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase; P5C
Product Background
Antigen Description
Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.
Pathway
4-hydroxyproline degradation I, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Citations
Publication ()
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COA
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