Anti-ALDH1L2 (aa 750-780) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse

Immunogen

Synthetic peptide within Human ALDH1L2 aa 750-780 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q3SY69

Conjugate

Application Notes

IHC-P: 1/50 - 1/100; WB: 1/100 - 1/500;

Alternative Names

ALDH1L2; aldehyde dehydrogenase 1 family, member L2; mtFDH; mitochondrial 10-formyltetrahydrofolate dehydrogenase; mitochondrial 10-FTHFDH; 10-formyltetrahydrofolate dehydrogenase ALDH1L2; aldehyde dehydrogenase family 1 member L2, mitochondrial; probable

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.

Pathway

One carbon pool by folate;