Anti-ALDH1L1 (aa 803-902) polyclonal antibody

Species Reactivity

Human

Immunogen

ALDH1L1 (NP_036322, 803 a.a. ~ 902 a.a) partial recombinant protein with GST tag. The sequence is EESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNT YNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY

Conjugate

Alternative Names

ALDH1L1; aldehyde dehydrogenase 1 family, member L1; FDH; FTHFD; 10-fTHF; 10-FTHFDH; cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.

Pathway

Folate-Alcohol and Cancer Pathway; One carbon pool by folate;