ALCAM (NP_001618, 28 a.a. ~ 137 a.a) partial recombinant protein with GST tag. The sequence is WYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYK DRLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKP
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Pathway
Axon guidance; Developmental Biology;
Citations
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