Synthetic peptide within Human AKR1C1 aa 290-304 (C terminal). The exact sequence is proprietary. Genbank: NP_001344Sequence: SEEMKAIDGLNRNVR Database link: Q04828
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50 - 1/200; WB: 1/500 - 1/2000.
Target
Alternative Names
AKR1C1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); DDH1; aldo-keto reductase family 1 member C1; DD1; DDH; HAKRC; MBAB; aldo-keto reductase C; indanol dehydrogenase; dihydrodiol
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Pathway
Metabolism of xenobiotics by cytochrome P450; Steroid hormone biosynthesis;
Citations
Publication ()
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COA
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