Specifications
Immunogen
Antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human AFAP1.
Target
Alternative Names
AFAP1; actin filament associated protein 1; AFAP; AFAP110; AFAP-110; actin filament-associated protein 1; 110 kDa actin filament-associated protein; actin filament-associated protein, 110 kDa
Product Background
Antigen Description
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Reynolds, AB; Kanner, SB; et al. SRChing for the substrates of Src. ONCOGENE 33:4537-4547(2014).
Dorfleutner, A; Cho, Y; et al. Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells. JOURNAL OF CELL SCIENCE 121:2394-2405(2008).
COA
Certificate of Analysis
