ADCY2 (NP_065433, 977 a.a. ~ 1086 a.a) partial recombinant protein with GST tag. The sequence is GKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQ VTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNVAS
Conjugate
Unconjugated
Target
Alternative Names
ADCY2; adenylate cyclase 2 (brain); AC2; HBAC2; adenylate cyclase type 2; adenylyl cyclase 2; adenylate cyclase II; ATP pyrophosphate-lyase 2; adenylate cyclase type II; type II adenylate cyclase; 3,5-cyclic AMP synthetase;
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
Pathway
Activation of GABAB receptors; Adenylate cyclase inhibitory pathway; Adrenergic signaling in cardiomyocytes; Bile secretion.
Citations
Publication ()
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