Rabbit Anti-Human ADAT2 (a.a. 33-193) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human ADAT2 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 33-193 aa of BC037955

Conjugate

Application Notes

WB: 1:500-1:1000
IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate
IHC: 1:50-1:500
IF/ICC: 1:20-1:200

General Notes

This product (Catalog No. DPABH-26070) is a rabbit-derived polyclonal antibody raised against human ADAT2, targeting the amino acid region 33–193 of the protein. This antibody exhibits cross-reactivity with Human ADAT2 from mouse and rat. It has been affinity purified by Protein A. ADAT2(tRNA-specific adenosine deaminase 2) is also named as DEADC1 and Belongs to the cytidine and deoxycytidylate deaminase family. It is a 24-kDa molecular mass protein that harbors all the conserved motifs required for deamination. ADAT2 and ADAT3 can function as a heterodimer which catalyses inosine formation at the wobble position (position 34) in eukaryotic tRNAs(PMID:12457566). It has 2 isoforms produced by alternative splicing.
DPABH-26070 is suitable for use in Western blot (WB) (1:500–1:1,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:50–1:500), IF/ICC (1:20–1:200) applications.
DPABH-26070 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

tRNA-specific adenosine deaminase 2; TAD2; EC:3.5.4.33; Deaminase domain-containing protein 1; DEADC1

Entrez Gene ID

UniProt ID