Recombinant human ADAM33 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 30-364 aa of BC125113
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:2000
General Notes
This product (Catalog No. DPABH-00819) is a rabbit-derived polyclonal antibody raised against human ADAM33, targeting the amino acid region 30–364 of the protein. It has been affinity purified by Protein A. ADAM33 is a member of the 'a disintegrin and metalloprotease domain' family of proteins. Endogenous ADAM33 is detected in bronchus tissue, bronchial smooth muscle cells, and MRC-5 fibroblasts, consistent with a role in the pathophysiology of asthma(PMID:12535637). ADAM33 is a novel tumour suppressor gene that may be useful as a molecular marker for invasive lobular carcinoma of the breast(PMID:19267929). DPABH-00819 is suitable for use in Western blot (WB) (1:500–1:2,000) application. DPABH-00819 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
UNQ873/PRO1891; EC:3.4.24.-; Disintegrin and metalloproteinase domain-containing protein 33; C20orf153; ADAM 33
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