Mouse myeloma cell line NS0-derived recombinant mouse ALK-1. Asp23-Pro119 Accession Number Q61288
Conjugate
Biotin
Applications
Application Notes
Western Blot 0.1 μg/mL; ELISA Capture 0.2-0.8 μg/mL; ELISA Detection 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DPABY-310 - DPABY-611
Target
Alternative Names
ACVRL1; activin A receptor, type II-like 1; Alk1; Acvrlk1; AI115505; AI427544; serine/threonine-protein kinase receptor R3; SKR3; TSR-I; activin receptor-like kinase 1; activin receptor-like kinase-1; TGF-B superfamily receptor type I;
ALKs 1-7 are type I serine/threonine kinase receptors for TGF-beta superfamily members. They undergo hetero-oligomerization with type II serine/threonine kinase receptors to transduce signals, usually through Smad proteins. Alk-1 binds TGF-beta and Alk-7 is thought to bind nodal.
Pathway
Id Signaling Pathway; TGF-beta Receptor Signaling Pathway; XPodNet - protein-protein interactions in the podocyte expanded by STRING;
Citations
Publication ()
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