Anti-ACTN4 monoclonal antibody (DCABH-112)

Rabbit anti-Human ACTN4 monoclonal antibody for WB, IP, IHC-P, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS3644(3)
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to residues on the N-terminus of Human alpha Actinin 4.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/100 - 1/250; ICC/IF: 1/100 - 1/250;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ACTN4; actinin, alpha 4; focal segmental glomerulosclerosis 1 , FSGS1; alpha-actinin-4; actinin alpha4 isoform; non-muscle alpha-actinin 4
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell-Cell communication, organism-specific biosystem;

Citations


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References


Michaud, JL; Stitt-Cavanaugh, E; et al. Mice with podocyte-specific overexpression of wild type alpha-actinin-4 are healthy controls for K256E-alpha-actinin-4 mutant transgenic mice. TRANSGENIC RESEARCH 19:285-289(2010).
Henderson, JM; Alexander, MP; et al. Patients with ACTN4 Mutations Demonstrate Distinctive Features of Glomerular Injury. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 20:961-968(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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