Specifications
Immunogen
Synthetic peptide corresponding to Actin aa 365-375 (C terminal). Attached to a Multiple Antigen Peptide (MAP) backboneSequence: SGPSIVHRKCF
Target
Alternative Names
ACTA1; actin, alpha 1, skeletal muscle; ACTA; actin, alpha skeletal muscle; alpha-actin-1; alpha skeletal muscle actin; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; CFTD1; CFTDM;
Product Background
Antigen Description
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Pathway
Caspase cascade in apoptosis, organism-specific biosystem; Hypothetical Network for Drug Addiction, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; RhoA signaling pathway, organism-specific biosystem; Signaling events mediated by focal adhesion kinase, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem;
Citations
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Stern-Straeter, J; Bonaterra, GA; et al. Impact of static magnetic fields on human myoblast cell cultures. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 28:907-917(2011).
Goebel, HH; Brockmann, K; et al. Actin-related myopathy without any missense mutation in the ACTA1 gene. JOURNAL OF CHILD NEUROLOGY 19:149-153(2004).