Anti-ACSM2A polyclonal antibody (DPABH-03028)

Rabbit anti-Human ACSM2A (aa 195-434) polyclonal antibody for ELISA, WB, IHC-P Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 195-434 of Human ACSM2A (BC125176).
Conjugate
Unconjugated

Applications


Application Notes
ELISA: 1/20000 - 1/80000; WB: 1/1000 - 1/2000; IHC-P: 1/100 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ACSM2A; acyl-CoA synthetase medium-chain family member 2A; ACSM2; A-923A4.1; acyl-coenzyme A synthetase ACSM2A, mitochondrial; butyrate--CoA ligase 2A
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro). The function about ACSM2A antigen include ATP binding; butyrate-CoA ligase activity; metal ion binding.
Pathway
Amino Acid conjugation; Butanoate metabolism; Conjugation of carboxylic acids; Metabolism.

Citations


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References


Ledo, N; Ko, YA; et al. Functional Genomic Annotation of Genetic Risk Loci Highlights Inflammation and Epithelial Biology Networks in CKD. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 26:692-714(2015).
Kochan, G; Pilka, ES; et al. Structural Snapshots for the Conformation-dependent Catalysis by Human Medium-chain Acyl-coenzyme A Synthetase ACSM2A. JOURNAL OF MOLECULAR BIOLOGY 388:997-1008(2009).

Custom Antibody Labeling


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