Anti-ACOT7 monoclonal antibody, clone FQS22428(C)

Antibody Isotype

IgG

Clone

FQS22428(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide corresponding to residues in Human ACOT7 (UniProt ID: O00154).

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IP: 1/100 - 1/500;

Alternative Names

ACOT7; acyl-CoA thioesterase 7; cytosolic acyl coenzyme A thioester hydrolase; ACH1; ACT; BACH; brain acyl CoA hydrolase; CTE II; hBACH; LACH1; MGC1126; CTE-IIa; acyl-CoA thioesterase 2; brain acyl-CoA hydrolase; acyl-CoA thioesterase, long chain; long ch

Entrez Gene ID

UniProt ID

Antigen Description

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.

Pathway

Biosynthesis of unsaturated fatty acids, organism-specific biosystem; Biosynthesis of unsaturated fatty acids, conserved biosystem; Fatty acid elongation, organism-specific biosystem; Fatty acid elongation, conserved biosystem.