Anti-ABCB6 (aa 743-842) polyclonal antibody

Species Reactivity

Human; Mouse; Rat

Immunogen

ABCB6 (NP_005680, 743 a.a. ~ 842 a.a) partial recombinant protein with GST tag. The sequence is KAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVVNADQILVIKDGCI VERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTMER

Conjugate

Alternative Names

ABCB6; ATP-binding cassette, sub-family B (MDR/TAP), member 6; ABC; LAN; PRP; DUH3; umat; ABC14; MTABC3; MCOPCB7; ATP-binding cassette sub-family B member 6, mitochondrial; mt-ABC transporter 3; P-glycoprotein-related protein; mitochondrial ABC transporte

Entrez Gene ID

UniProt ID

Antigen Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Pathway

ABC transporters; ABC-family proteins mediated transport; Transmembrane transport of small molecules;