Anti-A4GALT polyclonal antibody (DPABH-19923)

Rabbit anti-Human A4GALT (aa 215-264) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide, corresponding to a region within internal sequence amino acids 215-264 (VLNGAFLAFE RRHEFMALCM RDFVDHYNGW IWGHQGPQLL TRVFKKWCSI) of Human A4GALT (NP_059132).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
A4GALT; alpha 1,4-galactosyltransferase; alpha 1,4 galactosyltransferase (globotriaosylceramide synthase, P blood group); lactosylceramide 4-alpha-galactosyltransferase; A14GALT; CD77 synthase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Glycosphingolipid biosynthesis - globo series; Glycosphingolipid biosynthesis, globo-series, LacCer =>Gb4Cer; Metabolic pathways;

Citations


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References


Westman, JS; Thuresson, B; et al. Large Deletions Involving the Regulatory Upstream Regions of A4GALT Give Rise to Principally Novel P1PK Null Alleles. TRANSFUSION 52:42A-42A(2012).
Suchanowska, A; Kaczmarek, R; et al. A Single Point Mutation in the Gene Encoding Gb3/CD77 Synthase Causes a Rare Inherited Polyagglutination Syndrome. JOURNAL OF BIOLOGICAL CHEMISTRY 287:-(2012).

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