Anti-ART3 monoclonal antibody (DMABT-H13083)

Mouse anti-Human ART3 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
4B3
Species Reactivity
Human
Immunogen
ART3 (NP_001170, 29 a.a. ~ 138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
ART3; ADP-ribosyltransferase 3; ecto-ADP-ribosyltransferase 3; mono-ADP-ribosyltransferase; mono(ADP-ribosyl)transferase 3; NAD(P)(+)--arginine ADP-ribosyltransferase 3
Entrez Gene ID
UniProt ID

Product Background


Gene summary
ART3 (ADP-Ribosyltransferase 3) is a Protein Coding gene. Among its related pathways are NAD metabolism. GO annotations related to this gene include NAD+ ADP-ribosyltransferase activity and NAD(P)+-protein-arginine ADP-ribosyltransferase activity. An important paralog of this gene is ART1. This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene.
Antigen Description
Protein Symbol:Q13508-NAR3_HUMANRecommended name:Ecto-ADP-ribosyltransferase 3Protein Accession:Q13508Secondary Accessions:Q53XW3Q6FHT7Q8WVJ7Q93069Q96HL1Ecto-ADP-ribosyltransferase 3 is an enzyme that in humans is encoded by the ART3 gene. 0The function about ART3 antigen include NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; transferase activity; transferase activity, transferring glycosyl groups.

Citations


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References


Balducci, E; Horiba, K; et al. Selective expression of RT6 superfamily in human bronchial epithelial cells. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 21:337-346(1999).
Koch-Nolte, F; Glowacki, G; et al. Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation. CELLULAR IMMUNOLOGY 236:66-71(2005).

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