Anti-AQP8 monoclonal antibody (DMABT-H13075)

Mouse anti-Human AQP8 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
2G9
Species Reactivity
Human
Immunogen
AQP8 (AAH40630,2a.a. ~ 255 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
AQP8; aquaporin 8; aquaporin-8; AQP-8
Entrez Gene ID
UniProt ID

Product Background


Gene summary
AQP8 (Aquaporin 8) is a Protein Coding gene. Among its related pathways are Cellular Senescence and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include transporter activity and glycerol channel activity. An important paralog of this gene is AQP1. Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.
Antigen Description
Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea. Aquaporin-8 is a protein that in humans is encoded by the AQP8 gene. 0The function about AQP8 antigen include transporter activity; water channel activity.
Pathway
Aquaporin-mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Passive Transport by Aquaporins, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem.

Citations


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References


Calamita, G; Mazzone, A; et al. Expression and immunolocalization of the aquaporin-8 water channel in rat gastrointestinal tract. EUROPEAN JOURNAL OF CELL BIOLOGY 80:711-719(2001).
Hurley, PT; Ferguson, CJ; et al. Expression and immunolocalization of aquaporin water channels in rat exocrine pancreas. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 280:G701-G709(2001).

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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