Human ANAPC4 blocking peptide (CDBP0422)

Synthetic Human ANAPC4 blocking peptide for BL

Product Overview
Blocking peptide for anti-APC4 antibody
Target
APC4
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Function
protein binding; protein phosphatase binding; ubiquitin-protein ligase activity;
Synonyms
ANAPC4; anaphase promoting complex subunit 4; APC4; anaphase-promoting complex subunit 4; cyclosome subunit 4;

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References


Sliter, DA; Aguiar, M; et al. Activated Inositol 1,4,5-Trisphosphate Receptors Are Modified by Homogeneous Lys-48-and Lys-63-linked Ubiquitin Chains, but Only Lys-48-linked Chains Are Required for Degradation. JOURNAL OF BIOLOGICAL CHEMISTRY 286:1074-1082(2011).

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