Tag/Conjugate
Unconjugated
Purity
> 95 % by SDS-PAGE.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Reconstitution
APC2 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.
Introduction
APC2 might function in the Wnt signaling pathway through it's ability to promote the rapid degradation of beta-catenin. It also functions as a tumour suppressor.
Synonyms
APC2; adenomatosis polyposis coli 2; APCL; adenomatous polyposis coli protein 2; adenomatous polyposis coli like;
Citations
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Morgan, D; Eley, L; et al. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. HUMAN MOLECULAR GENETICS 11:3345-3350(2002).
Huang, JN; Sheung, J; et al. High-throughput screening for inhibitors of the E3 ubiquitin ligase APC. UBIQUITIN AND PROTEIN DEGRADATION, PT B 399:740-754(2005).
COA
Certificate of Analysis
